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Differential determinants for coupling of distinct G proteins with the class B secretin receptor
The secretin receptor is a prototypic class B G protein-coupled receptor that is activated by binding of its natural peptide ligand. The signaling effects of this receptor are mediated by coupling with Gs, which activates cAMP production, and Gq, which activates intracellular calcium mobilization. W...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330731/ https://ncbi.nlm.nih.gov/pubmed/22277758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00273.2011 |
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