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Prion Protein Misfolding

The crucial event in the development of transmissible spongiform encephalopathies (TSEs) is the conformational change of a host-encoded membrane protein - the cellular PrP(C) - into a disease associated, fibril-forming isoform PrP(Sc). This conformational transition from the α-helix-rich cellular fo...

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Bibliografski detalji
Glavni autori: Kupfer, L, Hinrichs, W, Groschup, M.H
Format: Artigo
Jezik:Inglês
Izdano: Bentham Science Publishers Ltd. 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330701/
https://ncbi.nlm.nih.gov/pubmed/19860662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/156652409789105543
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