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Prion Protein Misfolding
The crucial event in the development of transmissible spongiform encephalopathies (TSEs) is the conformational change of a host-encoded membrane protein - the cellular PrP(C) - into a disease associated, fibril-forming isoform PrP(Sc). This conformational transition from the α-helix-rich cellular fo...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers Ltd.
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330701/ https://ncbi.nlm.nih.gov/pubmed/19860662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/156652409789105543 |
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