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Synthesis, Biological Evaluation and Structure-Activity Relationships of N-Benzoyl-2-hydroxybenzamides as Agents Active against P. falciparum (K1 strain), Trypanosomes, and Leishmania

In our efforts to identify novel chemical scaffolds for the development of new antiprotozoal drugs, a compound library was screened against T. gondii tachyzoites with activity discovered for N-(4-ethylbenzoyl)-2-hydroxybenzamide 1a against T. gondii as described elsewhere.(1) Synthesis of a compound...

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Dettagli Bibliografici
Autori principali: Stec, Jozef, Huang, Qingqing, Pieroni, Marco, Kaiser, Marcel, Fomovska, Alina, Mui, Ernest, Witola, William H., Bettis, Samuel, McLeod, Rima, Brun, Reto, Kozikowski, Alan P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330251/
https://ncbi.nlm.nih.gov/pubmed/22352841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2015183
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