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Use of the gamma method for self-contained gene-set analysis of SNP data

Gene-set analysis (GSA) evaluates the overall evidence of association between a phenotype and all genotyped single nucleotide polymorphisms (SNPs) in a set of genes, as opposed to testing for association between a phenotype and each SNP individually. We propose using the Gamma Method (GM) to combine...

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Autors principals: Biernacka, Joanna M, Jenkins, Gregory D, Wang, Liewei, Moyer, Ann M, Fridley, Brooke L
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330217/
https://ncbi.nlm.nih.gov/pubmed/22166939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.236
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