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Use of the gamma method for self-contained gene-set analysis of SNP data
Gene-set analysis (GSA) evaluates the overall evidence of association between a phenotype and all genotyped single nucleotide polymorphisms (SNPs) in a set of genes, as opposed to testing for association between a phenotype and each SNP individually. We propose using the Gamma Method (GM) to combine...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3330217/ https://ncbi.nlm.nih.gov/pubmed/22166939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.236 |
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