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Self-Contained Gene-Set Analysis of Expression Data: An Evaluation of Existing and Novel Methods

Gene set methods aim to assess the overall evidence of association of a set of genes with a phenotype, such as disease or a quantitative trait. Multiple approaches for gene set analysis of expression data have been proposed. They can be divided into two types: competitive and self-contained. Benefit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fridley, Brooke L., Jenkins, Gregory D., Biernacka, Joanna M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941449/
https://ncbi.nlm.nih.gov/pubmed/20862301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012693
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