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Gene set analysis of SNP data: benefits, challenges, and future directions

The last decade of human genetic research witnessed the completion of hundreds of genome-wide association studies (GWASs). However, the genetic variants discovered through these efforts account for only a small proportion of the heritability of complex traits. One explanation for the missing heritab...

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Autori principali: Fridley, Brooke L, Biernacka, Joanna M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172936/
https://ncbi.nlm.nih.gov/pubmed/21487444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.57
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