Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo

The concentration of amyloid-β (Aβ) within the brain extracellular space is one determinant of whether the peptide will aggregate into toxic species that are important in Alzheimer's disease (AD) pathogenesis. Some types of synaptic activity can regulate Aβ levels. Here we demonstrate two disti...

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Detalles Bibliográficos
Main Authors: Verges, Deborah K., Restivo, Jessica L., Goebel, Whitney D., Holtzman, David M., Cirrito, John R.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329800/
https://ncbi.nlm.nih.gov/pubmed/21813692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0607-11.2011
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