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Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA Receptors In Vivo
The concentration of amyloid-β (Aβ) within the brain extracellular space is one determinant of whether the peptide will aggregate into toxic species that are important in Alzheimer's disease (AD) pathogenesis. Some types of synaptic activity can regulate Aβ levels. Here we demonstrate two disti...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Society for Neuroscience
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329800/ https://ncbi.nlm.nih.gov/pubmed/21813692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0607-11.2011 |
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