Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach

Eitemau Tebyg

• DISTINCT ROLES OF β1 MIDAS, ADMIDAS AND LIMBS CATION-BINDING SITES IN LIGAND RECOGNITION BY INTEGRIN α2β1
  gan: Valdramidou, Dimitra, et al.
  Cyhoeddwyd: (2008)
• DUAL FUNCTIONALITY OF THE ANTI-β1 INTEGRIN ANTIBODY, 12G10, EXEMPLIFIES AGONISTIC SIGNALLING FROM THE LIGAND-BINDING POCKET OF INTEGRIN ADHESION RECEPTORS
  gan: Humphries, Jonathan D., et al.
  Cyhoeddwyd: (2005)
• INTEGRIN LIGANDS
  gan: Humphries, Jonathan D., et al.
  Cyhoeddwyd: (2006)
• Ligand-induced Epitope Masking: DISSOCIATION OF INTEGRIN α5β1-FIBRONECTIN COMPLEXES ONLY BY MONOCLONAL ANTIBODIES WITH AN ALLOSTERIC MODE OF ACTION
  gan: Mould, A. Paul, et al.
  Cyhoeddwyd: (2016)
• Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.
  gan: Burrows, L, et al.
  Cyhoeddwyd: (1999)