A carregar...
Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach
Integrin α5β1 is a key receptor for the extracellular matrix protein fibronectin. Antagonists of human α5β1 have therapeutic potential as anti-angiogenic agents in cancer and diseases of the eye. However, the structure of the integrin is unsolved and the atomic basis of fibronectin and antagonist bi...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329623/ https://ncbi.nlm.nih.gov/pubmed/19747169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090992 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|