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DUAL FUNCTIONALITY OF THE ANTI-β1 INTEGRIN ANTIBODY, 12G10, EXEMPLIFIES AGONISTIC SIGNALLING FROM THE LIGAND-BINDING POCKET OF INTEGRIN ADHESION RECEPTORS
Although integrins are known to mediate connections between extracellular adhesion molecules and the intracellular actin cytoskeleton, the mechanisms that are responsible for coupling ligand binding to intracellular signalling, for generating diversity in signalling, and for determining the efficacy...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327468/ https://ncbi.nlm.nih.gov/pubmed/15632175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411102200 |
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