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LYP inhibits T cell activation when dissociated from CSK

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we studied the spatio-temporal dynamics of the LYP/CSK complex in T...

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Bibliografiske detaljer
Main Authors: Vang, Torkel, Liu, Wallace H., Delacroix, Laurence, Wu, Shuangding, Vasile, Stefan, Dahl, Russell, Yang, Li, Musumeci, Lucia, Francis, Dana, Landskron, Johannes, Tasken, Kjetil, Tremblay, Michel L., Lie, Benedicte A., Page, Rebecca, Mustelin, Tomas, Rahmouni, Souad, Rickert, Robert C., Tautz, Lutz
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329573/
https://ncbi.nlm.nih.gov/pubmed/22426112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.916
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