LYP inhibits T cell activation when dissociated from CSK

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we studied the spatio-temporal dynamics of the LYP/CSK complex in T...

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Detalhes bibliográficos
Main Authors: Vang, Torkel, Liu, Wallace H., Delacroix, Laurence, Wu, Shuangding, Vasile, Stefan, Dahl, Russell, Yang, Li, Musumeci, Lucia, Francis, Dana, Landskron, Johannes, Tasken, Kjetil, Tremblay, Michel L., Lie, Benedicte A., Page, Rebecca, Mustelin, Tomas, Rahmouni, Souad, Rickert, Robert C., Tautz, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329573/
https://ncbi.nlm.nih.gov/pubmed/22426112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.916
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