LYP inhibits T cell activation when dissociated from CSK

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we studied the spatio-temporal dynamics of the LYP/CSK complex in T...

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Autors principals: Vang, Torkel, Liu, Wallace H., Delacroix, Laurence, Wu, Shuangding, Vasile, Stefan, Dahl, Russell, Yang, Li, Musumeci, Lucia, Francis, Dana, Landskron, Johannes, Tasken, Kjetil, Tremblay, Michel L., Lie, Benedicte A., Page, Rebecca, Mustelin, Tomas, Rahmouni, Souad, Rickert, Robert C., Tautz, Lutz
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329573/
https://ncbi.nlm.nih.gov/pubmed/22426112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.916
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