Multidentate Small-Molecule Inhibitors of Vaccinia H1-related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer Cells

Loss of VHR phosphatase causes cell cycle arrest in HeLa carcinoma cells, suggesting that VHR inhibition may be a useful approach to halt the growth of cancer cells. We recently reported that VHR is upregulated in several cervix cancer cell lines as well as in carcinomas of the uterine cervix. Here...

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Detalhes bibliográficos
Main Authors: Wu, Shuangding, Vossius, Sofie, Rahmouni, Souad, Miletic, Ana V., Vang, Torkel, Vazquez-Rodriguez, Jesus, Cerignoli, Fabio, Arimura, Yutaka, Williams, Scott, Hayes, Tikva, Moutschen, Michel, Vasile, Stefan, Pellecchia, Maurizio, Mustelin, Tomas, Tautz, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790023/
https://ncbi.nlm.nih.gov/pubmed/19888758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901016k
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