Multidentate Small-Molecule Inhibitors of Vaccinia H1-related (VHR) Phosphatase Decrease Proliferation of Cervix Cancer Cells

Loss of VHR phosphatase causes cell cycle arrest in HeLa carcinoma cells, suggesting that VHR inhibition may be a useful approach to halt the growth of cancer cells. We recently reported that VHR is upregulated in several cervix cancer cell lines as well as in carcinomas of the uterine cervix. Here...

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Autors principals: Wu, Shuangding, Vossius, Sofie, Rahmouni, Souad, Miletic, Ana V., Vang, Torkel, Vazquez-Rodriguez, Jesus, Cerignoli, Fabio, Arimura, Yutaka, Williams, Scott, Hayes, Tikva, Moutschen, Michel, Vasile, Stefan, Pellecchia, Maurizio, Mustelin, Tomas, Tautz, Lutz
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790023/
https://ncbi.nlm.nih.gov/pubmed/19888758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901016k
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