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Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics

Chirality is an interesting topic and it is meaningful to explore the interactions between chiral small molecules and stereoselective biomacromolecules, with pre-clinical and clinical significances. We have previously demonstrated that 20(S)-ginsenoside Rh2 is an effective P-glycoprotein (P-gp) inhi...

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Detalhes bibliográficos
Main Authors: Zhang, Jingwei, Zhou, Fang, Niu, Fang, Lu, Meng, Wu, Xiaolan, Sun, Jianguo, Wang, Guangji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329467/
https://ncbi.nlm.nih.gov/pubmed/22530069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035768
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