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Ginsenoside Rh2 pretreatment and withdrawal reactivated the pentose phosphate pathway to ameliorate intracellular redox disturbance and promoted intratumoral penetration of adriamycin

Improving the limited penetration, accumulation and therapeutic effects of antitumor drugs in the avascular region of the tumor mass is crucial during chemotherapy. P-gp inhibitors have achieved little success despite significant efforts. Excessive P-gp inhibition disturbed the kinetic balance betwe...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Liu, Jiali, Cai, Qingyun, Wang, Wenjie, Lu, Meng, Liu, Jianming, Zhou, Fang, Sun, Minjie, Wang, Guangji, Zhang, Jingwei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7264470/
https://ncbi.nlm.nih.gov/pubmed/32067911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101452
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