Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics

Chirality is an interesting topic and it is meaningful to explore the interactions between chiral small molecules and stereoselective biomacromolecules, with pre-clinical and clinical significances. We have previously demonstrated that 20(S)-ginsenoside Rh2 is an effective P-glycoprotein (P-gp) inhi...

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Hlavní autoři: Zhang, Jingwei, Zhou, Fang, Niu, Fang, Lu, Meng, Wu, Xiaolan, Sun, Jianguo, Wang, Guangji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329467/
https://ncbi.nlm.nih.gov/pubmed/22530069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035768
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