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Cell density-dependent reduction of dihydroceramide desaturase activity in neuroblastoma cells

We applied a metabolic approach to investigate the role of sphingolipids in cell density-induced growth arrest in neuroblastoma cells. Our data revealed that sphingolipid metabolism in neuroblastoma cells significantly differs depending on the cells’ population context. At high cell density, cells e...

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Autors principals: Spassieva, Stefka D., Rahmaniyan, Mehrdad, Bielawski, Jacek, Clarke, Christopher J., Kraveka, Jacqueline M., Obeid, Lina M.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329391/
https://ncbi.nlm.nih.gov/pubmed/22377532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019075
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