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Analysis of the Inhibition and Remodeling of Islet Amyloid Polypeptide Amyloid Fibers by Flavanols

Islet amyloid polypeptide (IAPP, amylin) is responsible for amyloid formation in type 2 diabetes and in transplanted islets. The flavanol, (−)-Epigallocatechin-3-gallate [EGCG; (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl3,4,5-trihydroxybenzoate] is an effective...

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Bibliografiske detaljer
Main Authors: Cao, Ping, Raleigh, Daniel P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329122/
https://ncbi.nlm.nih.gov/pubmed/22409724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2015162
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