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Discovery and validation of new molecular targets in treating dyslipidemia: The role of human genetics
Several high profile failures of lipid-related therapeutics in clinical trials have led to intense interest in improved discovery and preclinical prioritization of potential targets. The careful study of patients with rare monogenic disorders has played a key role in establishing the causal role of...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328807/ https://ncbi.nlm.nih.gov/pubmed/20211435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.12.003 |
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