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Discovery and validation of new molecular targets in treating dyslipidemia: The role of human genetics

Several high profile failures of lipid-related therapeutics in clinical trials have led to intense interest in improved discovery and preclinical prioritization of potential targets. The careful study of patients with rare monogenic disorders has played a key role in establishing the causal role of...

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Detalhes bibliográficos
Main Authors: Khera, Amit V., Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328807/
https://ncbi.nlm.nih.gov/pubmed/20211435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.12.003
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