Bone Morphogenetic Protein-2-Induced Signaling and Osteogenesis Is Regulated by Cell Shape, RhoA/ROCK, and Cytoskeletal Tension

Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is classically thought to be mediated by different cytokines such as the bone morphogenetic proteins (BMPs). Here, we report that cell adhesion to extracellular matrix (ECM), and its effects on cell shape and cytoskeletal mechanics,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Yang-Kao, Yu, Xiang, Cohen, Daniel M., Wozniak, Michele A., Yang, Michael T., Gao, Lin, Eyckmans, Jeroen, Chen, Christopher S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2012
Aiheet:
Original Research Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328763/
https://ncbi.nlm.nih.gov/pubmed/21967638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2011.0293
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