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ACTIVATION OF ROCK BY RHOA IS REGULATED BY CELL ADHESION, SHAPE, AND CYTOSKELETAL TENSION
Adhesion to the extracellular matrix regulates numerous changes in the actin cytoskeleton by regulating the activity of the Rho family of small GTPases. Here, we report that adhesion, and the associated changes in cell shape and cytoskeletal tension, are all required for GTP-bound RhoA to activate i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064860/ https://ncbi.nlm.nih.gov/pubmed/17673200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.07.002 |
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