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An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling
Focal adhesion kinase (FAK) transduces cell adhesion to the extracellular matrix into proliferative signals. We show that FAK overexpression induced proliferation in endothelial cells, which are normally growth arrested by limited adhesion. Interestingly, displacement of FAK from adhesions by using...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064187/ https://ncbi.nlm.nih.gov/pubmed/16847103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200510062 |
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