Low Folding Cooperativity of Hp35 Revealed by Single-Molecule Force Spectroscopy and Molecular Dynamics Simulation

Some small proteins, such as HP35, fold at submicrosecond timescale with low folding cooperativity. Although these proteins have been extensively investigated, still relatively little is known about their folding mechanism. Here, using single-molecule force spectroscopy and steered molecule dynamics...

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Bibliografiske detaljer
Main Authors: Lv, Chunmei, Tan, Cheng, Qin, Meng, Zou, Dawei, Cao, Yi, Wang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2012
Fag:
Protein
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328709/
https://ncbi.nlm.nih.gov/pubmed/22768951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.028
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