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Low Folding Cooperativity of Hp35 Revealed by Single-Molecule Force Spectroscopy and Molecular Dynamics Simulation

Some small proteins, such as HP35, fold at submicrosecond timescale with low folding cooperativity. Although these proteins have been extensively investigated, still relatively little is known about their folding mechanism. Here, using single-molecule force spectroscopy and steered molecule dynamics...

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Main Authors: Lv, Chunmei, Tan, Cheng, Qin, Meng, Zou, Dawei, Cao, Yi, Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328709/
https://ncbi.nlm.nih.gov/pubmed/22768951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.03.028
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