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Tackling Force-Field Bias in Protein Folding Simulations: Folding of Villin HP35 and Pin WW Domains in Explicit Water

The ability to fold proteins on a computer has highlighted the fact that existing force fields tend to be biased toward a particular type of secondary structure. Consequently, force fields for folding simulations are often chosen according to the native structure, implying that they are not truly “t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mittal, Jeetain, Best, Robert B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913180/
https://ncbi.nlm.nih.gov/pubmed/20682244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.005
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