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Common Structural Transitions in Explicit-Solvent Simulations of Villin Headpiece Folding

Molecular dynamics simulations of protein folding can provide very high-resolution data on the folding process; however, due to computational challenges most studies of protein folding have been limited to small peptides, or made use of approximations such as Gō potentials or implicit solvent models...

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Detalhes bibliográficos
Main Authors: Freddolino, Peter L., Schulten, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764099/
https://ncbi.nlm.nih.gov/pubmed/19843466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.012
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