Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2)

AIMS/HYPOTHESIS: Rapamycin (sirolimus) is one of the primary immunosuppressants for islet transplantation. Yet there is evidence that the long-term treatment of islet-transplant patients with rapamycin may be responsible for subsequent loss of islet graft function and viability. Therefore, the prima...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Barlow, A. D., Xie, J., Moore, C. E., Campbell, S. C., Shaw, J. A. M., Nicholson, M. L., Herbert, T. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328678/
https://ncbi.nlm.nih.gov/pubmed/22314813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2475-7
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados