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Exogenous Amino Acids Are Essential for Interleukin-7 Induced CD8 T Cell Gowth

IL-7 signalling is important in regulating both survival and cellular size (growth) of T cells. While glucose metabolism has previously been implicated in the mechanism of IL-7 induced survival and growth, the role of amino acids has not before been reported. Here, we show IL-7 dependent T cell surv...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pearson, Claire, Silva, Ana, Seddon, Benedict
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328464/
https://ncbi.nlm.nih.gov/pubmed/22529903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033998
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