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Zap70 is essential for long-term survival of naive CD8 T cells

Survival of naive T cells requires engagement of T cell receptor (TCR) with self-peptide major histocompatibility antigens. The signalling pathways required to transmit this survival signal are poorly understood. Here, we ask whether the tyrosine kinase Zap70 is required to transmit survival signals...

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Detaylı Bibliyografya
Asıl Yazarlar: van der Loeff, Ina Schim, Hsu, Lih-Yun, Saini, Manoj, Weiss, Art, Seddon, Benedict
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167606/
https://ncbi.nlm.nih.gov/pubmed/25092893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400858
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