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Zap70 is essential for long-term survival of naive CD8 T cells
Survival of naive T cells requires engagement of T cell receptor (TCR) with self-peptide major histocompatibility antigens. The signalling pathways required to transmit this survival signal are poorly understood. Here, we ask whether the tyrosine kinase Zap70 is required to transmit survival signals...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4167606/ https://ncbi.nlm.nih.gov/pubmed/25092893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400858 |
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