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Regulatory T Cells in the Control of Autoimmunity: the Essential Role of  Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4(+)CD45RC(−) Cells and CD4(+)CD8(−) Thymocytes

Previous studies have shown that induction of autoimmune diabetes by adult thymectomy and split dose irradiation of PVG.RT1(u) rats can be prevented by their reconstitution with peripheral CD4(+)CD45RC(−)TCR-α/β(+)RT6(+) cells and CD4(+)CD8(−) thymocytes from normal syngeneic donors. These data prov...

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Hlavní autoři: Seddon, Benedict, Mason, Don
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192980/
https://ncbi.nlm.nih.gov/pubmed/9892610
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