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Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4(+)CD45RC(−) Cells and CD4(+)CD8(−) Thymocytes
Previous studies have shown that induction of autoimmune diabetes by adult thymectomy and split dose irradiation of PVG.RT1(u) rats can be prevented by their reconstitution with peripheral CD4(+)CD45RC(−)TCR-α/β(+)RT6(+) cells and CD4(+)CD8(−) thymocytes from normal syngeneic donors. These data prov...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
1999
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192980/ https://ncbi.nlm.nih.gov/pubmed/9892610 |
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