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Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system

It has long been recognized that the T-cell compartment has more CD4 helper than CD8 cytotoxic T cells, and this is most evident looking at T-cell development in the thymus. However, it remains unknown how thymocyte development so favors CD4 lineage development. To identify the basis of this asymmet...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sinclair, Charles, Bains, Iren, Yates, Andrew J., Seddon, Benedict
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732981/
https://ncbi.nlm.nih.gov/pubmed/23858460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304859110
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