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Asymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune system
It has long been recognized that the T-cell compartment has more CD4 helper than CD8 cytotoxic T cells, and this is most evident looking at T-cell development in the thymus. However, it remains unknown how thymocyte development so favors CD4 lineage development. To identify the basis of this asymmet...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732981/ https://ncbi.nlm.nih.gov/pubmed/23858460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304859110 |
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