Quantifying and Predicting the Effect of Exogenous Interleukin-7 on CD4(+)T Cells in HIV-1 Infection

Exogenous Interleukin-7 (IL-7), in supplement to antiretroviral therapy, leads to a substantial increase of all CD4(+) T cell subsets in HIV-1 infected patients. However, the quantitative contribution of the several potential mechanisms of action of IL-7 is unknown. We have performed a mathematical...

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Detalhes bibliográficos
Main Authors: Thiébaut, Rodolphe, Drylewicz, Julia, Prague, Mélanie, Lacabaratz, Christine, Beq, Stéphanie, Jarne, Ana, Croughs, Thérèse, Sekaly, Rafick-Pierre, Lederman, Michael M., Sereti, Irini, Commenges, Daniel, Lévy, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031052/
https://ncbi.nlm.nih.gov/pubmed/24853554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003630
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