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Predictive Modeling of Chemical Hazard by Integrating Numerical Descriptors of Chemical Structures and Short-term Toxicity Assay Data

Quantitative structure-activity relationship (QSAR) models are widely used for in silico prediction of in vivo toxicity of drug candidates or environmental chemicals, adding value to candidate selection in drug development or in a search for less hazardous and more sustainable alternatives for chemi...

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Bibliografski detalji
Glavni autori: Rusyn, Ivan, Sedykh, Alexander, Low, Yen, Guyton, Kathryn Z., Tropsha, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327873/
https://ncbi.nlm.nih.gov/pubmed/22387746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs095
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