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Integrative Approaches for Predicting in vivo Effects of Chemicals from their Structural Descriptors and the Results of Short-term Biological Assays

Cheminformatics approaches such as Quantitative Structure Activity Relationship (QSAR) modeling have been used traditionally for predicting chemical toxicity. In recent years, high throughput biological assays have been increasingly employed to elucidate mechanisms of chemical toxicity and predict t...

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Vydáno v:Curr Top Med Chem
Hlavní autoři: Low, Yen S., Sedykh, Alexander, Rusyn, Ivan, Tropsha, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344042/
https://ncbi.nlm.nih.gov/pubmed/24805064
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