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Integrative Approaches for Predicting in vivo Effects of Chemicals from their Structural Descriptors and the Results of Short-term Biological Assays

Cheminformatics approaches such as Quantitative Structure Activity Relationship (QSAR) modeling have been used traditionally for predicting chemical toxicity. In recent years, high throughput biological assays have been increasingly employed to elucidate mechanisms of chemical toxicity and predict t...

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Detalles Bibliográficos
Publicado en:Curr Top Med Chem
Main Authors: Low, Yen S., Sedykh, Alexander, Rusyn, Ivan, Tropsha, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344042/
https://ncbi.nlm.nih.gov/pubmed/24805064
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