Histone Deacetylase 6 Associates With Ribosomes and Regulates De Novo Protein Translation During Arsenite Stress

Histone deacetylase 6 (HDAC6) is known as a cytoplasmic enzyme that regulates cell migration, cell adhesion, and degradation of misfolded proteins by deacetylating substrates such as α-tubulin and Hsp90. When HaCaT keratinocytes were exposed to 1–200μM sodium arsenite, we observed perinuclear locali...

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Detaylı Bibliyografya
Asıl Yazarlar: Kappeler, Kyle V., Zhang, Jack, Dinh, Thai Nho, Strom, Joshua G., Chen, Qin M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Molecular Toxicology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327865/
https://ncbi.nlm.nih.gov/pubmed/22367689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs070
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