MeCP2 binds to nucleosome free (linker DNA) regions and to H3K9/H3K27 methylated nucleosomes in the brain

Methyl-CpG-binding protein 2 (MeCP2) is a chromatin-binding protein that mediates transcriptional regulation, and is highly abundant in brain. The nature of its binding to reconstituted templates has been well characterized in vitro. However, its interactions with native chromatin are less understoo...

詳細記述

保存先:
書誌詳細
主要な著者: Thambirajah, Anita A., Ng, Marlee K., Frehlick, Lindsay J., Li, Andra, Serpa, Jason J., Petrotchenko, Evgeniy V., Silva-Moreno, Begonia, Missiaen, Kristal K., Borchers, Christoph H., Adam Hall, J., Mackie, Ryan, Lutz, Frank, Gowen, Brent E., Hendzel, Michael, Georgel, Philippe T., Ausió, Juan
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
Gene Regulation, Chromatin and Epigenetics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326294/
https://ncbi.nlm.nih.gov/pubmed/22144686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1066
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