The Role of Antigen Cross-Presentation From Leukemia Blasts on Immunity to the Leukemia-Associated Antigen PR1

Cross-presentation is an important mechanism by which exogenous tumor antigens are presented to elicit immunity. Since neutrophil elastase (NE) and proteinase-3 (P3) expression is increased in myeloid leukemia, we investigated whether NE and P3 are cross-presented by dendritic cells (DC) and B-cells...

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Main Authors: Alatrash, Gheath, Ono, Yoko, Sergeeva, Anna, Sukhumalchandra, Pariya, Zhang, Mao, St. John, Lisa S., Yang, Tian-Hui, Ruisaard, Kathryn, Armistead, Paul M., Mittendorf, Elizabeth A., He, Hong, Qiao, Na, Rodriguez-Cruz, Tania, Liang, Shoudan, Clise-Dwyer, Karen, Wieder, Eric D., Lizee, Gregory, Lu, Sijie, Molldrem, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326226/
https://ncbi.nlm.nih.gov/pubmed/22495388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31824b3b14
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