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Improved readout precision of the Bicoid morphogen gradient by early decoding

Transcription factors (TFs) bind to specific DNA sequences to induce or repress gene expression. Expression levels can be tuned by changing TF concentrations, but the precision of such tuning is limited, since the fraction of time a TF occupies its binding site is subject to stochastic fluctuations....

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Hlavní autoři: Tamari, Zvi, Barkai, Naama
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326149/
https://ncbi.nlm.nih.gov/pubmed/23449375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-011-9250-8
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