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Improved readout precision of the Bicoid morphogen gradient by early decoding

Transcription factors (TFs) bind to specific DNA sequences to induce or repress gene expression. Expression levels can be tuned by changing TF concentrations, but the precision of such tuning is limited, since the fraction of time a TF occupies its binding site is subject to stochastic fluctuations....

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Detalhes bibliográficos
Main Authors: Tamari, Zvi, Barkai, Naama
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326149/
https://ncbi.nlm.nih.gov/pubmed/23449375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-011-9250-8
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