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Physical aspects of precision in genetic regulation

The process by which transcription factors (TFs) locate specific DNA binding sites is stochastic and as such, is subject to a considerable level of noise. TFs diffuse in the three-dimensional nuclear space, but can also slide along the DNA. It was proposed that this sliding facilitates the TF molecu...

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Detalhes bibliográficos
Main Authors: Tamari, Zvi, Barkai, Naama, Fouxon, Itzhak
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047200/
https://ncbi.nlm.nih.gov/pubmed/22379230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-010-9208-2
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