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Scaling of morphogen gradients by an expansion-repression integral feedback control

Despite substantial size variations, proportions of the developing body plan are maintained with a remarkable precision. Little is known about the mechanisms that ensure this adaptation (scaling) of pattern with size. Most models of patterning by morphogen gradients do not support scaling. In contra...

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Autori principali: Ben-Zvi, Danny, Barkai, Naama
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872437/
https://ncbi.nlm.nih.gov/pubmed/20356830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912734107
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