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Threshold responses to morphogen gradients by zero-order ultrasensitivity

Translating a graded morphogen distribution into tight response borders is central to all developmental processes. Yet, the molecular mechanisms generating such behavior are poorly understood. During patterning of the Drosophila embryonic ventral ectoderm, a graded mitogen-activated protein kinase (...

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Detalhes bibliográficos
Main Authors: Melen, Gustavo J, Levy, Sagi, Barkai, Naama, Shilo, Ben-Zion
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681448/
https://ncbi.nlm.nih.gov/pubmed/16729063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100036
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