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Threshold responses to morphogen gradients by zero-order ultrasensitivity

Translating a graded morphogen distribution into tight response borders is central to all developmental processes. Yet, the molecular mechanisms generating such behavior are poorly understood. During patterning of the Drosophila embryonic ventral ectoderm, a graded mitogen-activated protein kinase (...

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Bibliografiske detaljer
Main Authors: Melen, Gustavo J, Levy, Sagi, Barkai, Naama, Shilo, Ben-Zion
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681448/
https://ncbi.nlm.nih.gov/pubmed/16729063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100036
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