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Threshold responses to morphogen gradients by zero-order ultrasensitivity

Translating a graded morphogen distribution into tight response borders is central to all developmental processes. Yet, the molecular mechanisms generating such behavior are poorly understood. During patterning of the Drosophila embryonic ventral ectoderm, a graded mitogen-activated protein kinase (...

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Autors principals: Melen, Gustavo J, Levy, Sagi, Barkai, Naama, Shilo, Ben-Zion
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681448/
https://ncbi.nlm.nih.gov/pubmed/16729063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100036
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