The NF-kappa B transcription factor induces DNA bending which is modulated by its 65-kD subunit.
This study describes a novel functional property of the eukaryotic transcription factor NF-kappa B in altering the DNA structure. We observed that the binding of purified NF-kappa B to DNA was facilitated by spermine and cations which are known to promote DNA bending, and by a nick in one position a...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1990
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332601/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174540/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.22.6497 |
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