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The NF-kappa B transcription factor induces DNA bending which is modulated by its 65-kD subunit.

This study describes a novel functional property of the eukaryotic transcription factor NF-kappa B in altering the DNA structure. We observed that the binding of purified NF-kappa B to DNA was facilitated by spermine and cations which are known to promote DNA bending, and by a nick in one position a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Schreck, R, Zorbas, H, Winnacker, E L, Baeuerle, P A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1990
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.22.6497
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