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The NF-kappa B transcription factor induces DNA bending which is modulated by its 65-kD subunit.

This study describes a novel functional property of the eukaryotic transcription factor NF-kappa B in altering the DNA structure. We observed that the binding of purified NF-kappa B to DNA was facilitated by spermine and cations which are known to promote DNA bending, and by a nick in one position a...

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Détails bibliographiques
Auteurs principaux: Schreck, R, Zorbas, H, Winnacker, E L, Baeuerle, P A
Format: Artigo
Langue:Inglês
Publié: 1990
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC332601/
https://ncbi.nlm.nih.gov/pubmed/2174540
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