Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

Mitochondria are best known as the essential intracellular organelles that host the homeostasis required for cellular survival, but they also have relevance in diverse disease-related conditions, including Alzheimer's disease (AD). Amyloid β (Aβ) peptide is the key molecule in AD pathogenesis,...

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Bibliographische Detailangaben
Hauptverfasser: Cha, Moon-Yong, Han, Sun-Ho, Son, Sung Min, Hong, Hyun-Seok, Choi, Young-Ju, Byun, Jayoung, Mook-Jung, Inhee
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325919/
https://ncbi.nlm.nih.gov/pubmed/22514691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034929
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